Explain how the collecting duct and anti-diuretic hormone regulates the volume and concentration of urine

Explain how the

regulates the volume and concentration of urine

32 Explain how the collecting duct and anti-diuretic hormone regulate the volume and concentration of urine

Isabella Plasencia

Human Anatomy and Physiology II

Course Number: BSC 2086C

Dr. Tamara Smith

December 10, 2021

Claimed Topic:

Explain how the collecting duct and antidiuretic hormone regulates the volume and concentration of urine


The distal convoluted tubule and the collecting duct reabsorb fluctuating volumes of liquid and salts and are controlled by various hormones especially aldosterone, natriuretic peptide, antidiuretic hormone, and parathyroid hormone (Saladin, 2020, p.907). The antidiuretic hormone accelerates water to reabsorb to stimulate the inclusion of what is called “water channels” into kidney tubules. The water goes through tubular cells and into the blood and causes a reduction in plasma osmolarity but an enhanced osmolarity of urine (Vivo, 2021). In the distal convoluted tubule there and the collecting duct, there are two forms of cells which are the principal cells and the intercalated cells. In these two forms of cells, there are different functions. The principal cells are plentiful, and have receptors, and are participating in water and salt stability. The intercalated cells do not have as many of the principal cells. The intercalated cells reabsorb K+ and produce H+ into the tubule. The antidiuretic hormone enhances the absorbency to the water of the distal convoluted tubule and collecting duct and affects increased water retaining and reduces the volume of urine. The distal convoluted tubule and collecting duct are two sections of the kidney nephron and are very important. Fluid in the distal convoluted tubule and collecting duct contains 20 percent of water and 7% of the salts from the glomerular filtrate (Saladin, 2020, p.907).

Critical Thinking:

This topic on how the collecting duct and how the antidiuretic hormone regulates the volume and concentration of urine is a fascinating topic to learn about. This is a topic I knew about but was not informed as much as I know now as I researched this topic. I learned a lot on this topic, and I encourage others to learn and engage in this topic. I find it very interesting how the convoluted tubule can be damaged, causing cell death. The human body works mysteriously interesting.



Saladin, K.S., Gan, C.A., & Cushman, H. N. (2020). Anatomy & Physiology: The unity of form and function (9th ed.). New York, NY: McGraw Hill Education.

Antidiuretic hormone. (n.d.). Retrieved December 10, 2021, from


Libre texts. (2020, August 14). 24.4c: Regulation of Urine Concentration and volume. Medicine

Libre Texts. Retrieved December 11, 2021, from



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hey i have to respond back to this post here is example how i have to write back

#27 Describe the process by which the kidney filters the blood plasma, including the relevant cellular structure of the glomerulus.

Hi teacher, Tamara.

The nephron is responsible for eliminating waste products, lost ions, and excess water in the blood, the blood that travels through the glomerulus at the moment that the heart pumps the blood, the pressure that it exerts pumps the small molecules that pass through the capillaries to the glomerular capsule this is the physical function of the nephron the ultrafiltrate travels through a series of curved tubules these cells that located on each side of the tube have different molecules that they like to absorb, the molecules that are excreted remain in the tubule while the water, the glucose return to the bloodstream. When the ultrafiltrated descends through the tubules, the cells become more hypertonic compared to the ultrafiltrate. This leads to a maximum amount of water being removed from the ultrafiltrate before leaving the nephron. This blood surrounds the nephron returns to the body through the interlobular vein free of toxins and excess substances. (Function of a Nephron, 2017)

Blood within the glomerulus creates glomerular hydrostatic pressure that forces fluid out of the glomerulus and into the glomerular capsule. The fluid in the glomerular capsule exerts a pressure that forces the fluid out of the glomerular capsule into the glomerulus, opposing the glomerular hydrostatic pressure.
In hypertension, glomerular capillary pressure tends to increase because at this time the reduction in afferent arteriolar resistance is greater than the reduction in efferent resistance. (Wilson, 2019)


Wilson, M. (2019). How is blood pressure built up in glomerulus? https://www.restaurantnorman.com/how-is-blood-pressure-built-up-in-glomerulus/.

Function of a Nephron. (2017). https://biologydictionary.net/nephron/.

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